| 18F-053 |
National epidemiologic study of complex regional pain syndrome in Korea.
Department of Anesthesiology and Pain
Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
Introduction
Although social burden for complex regional pain syndrome (CRPS) is crucial clinical issue, epidemiological evidence is still limited due to complexed decision process. This study aimed to investigate the updated epidemiology of CRPS in Korea using National Health Insurance Data.
Methods
KCD codes for CRPS together with CRPS national registry has been used to define CRPS cohort from 2009 until 2016. CRPS was divided into CRPS type 1 and type 2. CRPS registry was established as registering a new patient of CRPS and registry began to be cumulated from 2009. Primary outcome was investigating overall incidence rate for CRPS, and secondary outcome was annual trend of incidence rate of each CRPS types, and investigating affecting factors including age, gender, area and level of hospitals for annual trend of each CRPS incidence rate. For statistical analysis, chi-square test, linear and logistic linear regression test were conducted.
Results
A total of 122,210 of patients were registered during observation duration. Overall incidence of CRPS was 15.83 per 100,000 people in Korea (type1, 19.5; type2, 12.1, respectively). Overall trend of CRPS incidence showed a significantly decreasing trend. Among the two types, annual trend of CRPS type 2 showed sharper decrease in its incidence rate (p<0.01). Among the total CRPS, the proportion of CRPS type 1 (61.7%) was more common than that of type 2 (38.3%), and female proportion was larger in both type of disease. Most common affected age group per year was over sixties in both CRPS type 1 and 2 and also in both sexes (P < 0.05, respectively). There was no significant association between sex or hospital level with annual trend of CRPS incidence rate. However, non-Metropolitan area showed significant association with higher decreasing trend of CRPS incidnece rate compared with Seoul area in both CRPS types.
Conclusions
This is the first epidemiological study of CRPS using national registry set. Overall incidence of CRPS in Korea was 15.83 per 100,000 people and showed decreasing trend in all age groups. Further studies are needed to investigate the relationship between trend of incidence rate and age structural change, and also needed to investigate the socioeconomic burden of CRPS in Korea.
Although social burden for complex regional pain syndrome (CRPS) is crucial clinical issue, epidemiological evidence is still limited due to complexed decision process. This study aimed to investigate the updated epidemiology of CRPS in Korea using National Health Insurance Data.
Methods
KCD codes for CRPS together with CRPS national registry has been used to define CRPS cohort from 2009 until 2016. CRPS was divided into CRPS type 1 and type 2. CRPS registry was established as registering a new patient of CRPS and registry began to be cumulated from 2009. Primary outcome was investigating overall incidence rate for CRPS, and secondary outcome was annual trend of incidence rate of each CRPS types, and investigating affecting factors including age, gender, area and level of hospitals for annual trend of each CRPS incidence rate. For statistical analysis, chi-square test, linear and logistic linear regression test were conducted.
Results
A total of 122,210 of patients were registered during observation duration. Overall incidence of CRPS was 15.83 per 100,000 people in Korea (type1, 19.5; type2, 12.1, respectively). Overall trend of CRPS incidence showed a significantly decreasing trend. Among the two types, annual trend of CRPS type 2 showed sharper decrease in its incidence rate (p<0.01). Among the total CRPS, the proportion of CRPS type 1 (61.7%) was more common than that of type 2 (38.3%), and female proportion was larger in both type of disease. Most common affected age group per year was over sixties in both CRPS type 1 and 2 and also in both sexes (P < 0.05, respectively). There was no significant association between sex or hospital level with annual trend of CRPS incidence rate. However, non-Metropolitan area showed significant association with higher decreasing trend of CRPS incidnece rate compared with Seoul area in both CRPS types.
Conclusions
This is the first epidemiological study of CRPS using national registry set. Overall incidence of CRPS in Korea was 15.83 per 100,000 people and showed decreasing trend in all age groups. Further studies are needed to investigate the relationship between trend of incidence rate and age structural change, and also needed to investigate the socioeconomic burden of CRPS in Korea.
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